provides a comprehensive look at the who, what, when and how of Wegener's granulomatosis
Wegener's granulomatosis definition - medical term
An uncommon type of inflammation
of small arteries and veins (vasculitis) that classically involves
the vessels supplying the tissues of the lungs, nasal passages
(sinuses), and kidneys.
Wegener's granulomatosis usually affects young or middle-aged
adults.
Symptoms include fatigue, weight loss, fever, shortness of breath,
bloody sputum, joint pains, and sinus inflammation, sometimes with
nasal ulcerations and bloody nasal discharge.
The diagnosis of Wegener's granulomatosis is confirmed by finding
evidence of vasculitis and abnormal cellular formations called
granulomas on biopsy of tissue involved by the inflammatory
process.
Wegener's granulomatosis is a serious disease. Without treatment,
it can be fatal within months. Treatment is directed toward stopping
the inflammation process by suppressing the immune system.
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