A blood test for syphilis (VDRL
stands for Venereal Disease Research Laboratory) that detects an
antibody that is present in the bloodstream when a patient has
syphilis.
A negative (nonreactive) VDRL is compatible with a
person not having syphilis, but in the early stages of the disease,
the VDRL often gives false negative results. Conversely, a false
positive VDRL can be encountered in infectious mononucleosis, lupus,
antiphospholipid antibody syndrome, hepatitis A, leprosy, malaria
and, occasionally, pregnancy.
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