Neuron-specific enolase (NSE) definition - medical term
Neuron-specific enolase
(NSE) is a substance that has been detected in patients with certain
tumors, namely: neuroblastoma, small cell lung cancer, medullary
thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and
melanoma.
Studies of NSE as a tumor marker have concentrated primarily on
patients with neuroblastoma and small cell lung cancer. Measurement
of NSE levels in patients with these two diseases can provide
information about the extent of the disease and the patient's
prognosis (outlook), as well as about the patient's response to
treatment.
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