Meningitis, cryptococcal definition - medical term
Inflammation of the
meninges due to infection with the fungal organism
cryptococcus neoformans, which is found mainly in dirt and
bird droppings. Most people have been exposed to this
organism at some time, but normally it causes no problems.
Often associated with AIDS, cryptococcal meningitis is
considered an opportunistic infection: a disease that
emerges most often when the immune system is compromised in
some way. Diagnosis is by observation of symptoms, lumbar
puncture, and cryptococcal titer. Treatment takes place in
the hospital, and usually consists of intravenous doses of
the antibiotic amphotericin B. Once the infection is under
control, patients usually remain on a maintenance dose of
fluconazole (DIFLUCAN) to prevent re-infection.
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