provides a comprehensive look at the who, what, when and how of Melanosis coli
Melanosis coli (Pseudomelanosis coli) definition - medical term
A benign, reversible
condition usually, but not always, associated with long-term use of anthranoid
laxatives in which pigment deposition in the lamina propria of the large intestine results
in a brown to black discoloration of the mucosa (lining) of the
large intestine. Melanosis coli is sometimes called pseudomelanosis coli since
the pigment deposited is lipofuscin and not melanin as the name implies.
Melanosis coli produces no symptoms and is indicative of chronic laxative use.
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