The age of the mother at the time of delivery. Advanced maternal age is usually defined as age 35 or more at delivery.
A
dvanced maternal age predisposes to Down syndrome (trisomy 21). The risk of having a Down syndrome baby rises with maternal age. It essentially doubles from 1 in 725 at maternal age 32 to 1 in 365 at maternal age 35. And the risk continues to climb with the years and is 1 in 32 at maternal age 45.
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