Disease of the large blood vessels, including the
coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs.
Macrovascular disease is by contrast to microvascular disease. In persons with diabetes,
chronic hyperglycemia (assessed by glycosylated hemoglobin level) is related to
the development of microvascular disease; however, the relation of glycosylated
hemoglobin to macrovascular disease is less clear.
Common Misspellings: macrovascular diease, macrovascular desease
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