A process used to filter and remove white blood cells
from whole blood before transfusion. The reason why white blood cells (leukocytes)
are removed from blood is because they provide no benefit to the recipient but can
carry bacteria and viruses to the recipient. Patients who receive blood that has
not been leukoreduced may have adverse effects, including fever with chills; alloimmunization,
an immune system reaction which can compromise a later transfusion; and the transmission
of viruses including cytomegalovirus (CMV) which can be dangerous for low-birth
weight infants and to transplant patients.
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