A to Z medical terms definitions (medical terminology dictionary )
|
A |
B |
C |
D |
E |
F |
G |
H |
I |
J |
K |
L |
M |
N |
O |
P |
Q | |
R |
S |
T |
U |
V |
W |
X |
Y |
Z |
Definition of Lamin A-C
Lamin A-C-
The lamin family of proteins that make up the nuclear lamina,
a matrix of protein located next to the inner nuclear membrane. Also known as LMNA.
Lamin proteins are involved in nuclear stability, chromatin structure and gene expression.
There are two types of mammalian lamin, A and B. Through alternate splicing, this
gene encodes three type A lamin isoforms.
M utations in the lamin A-C gene lead to a number of diseases- Emery-Dreifuss
muscular dystrophy type 2, familial partial lipodystrophy, limb girdle muscular
dystrophy type 1B, dilated cardiomyopathy, familial partial lipodystrophy, Charcot-Marie-Tooth
disorder type 2B1, mandibuloacral dysplasia, childhood progeria syndrome (Hutchinson-Gilford
syndrome) and a subset of Werner syndrome. These diseases have therefore been referred
to as laminopathies.
medical
dictionary, online medical dictionary, medical terminology
dictionary, free online medical dictionary, medical
dictionary, online medical dictionary, medical terminology
dictionary, free online medical dictionary, dictionary
medical, dictionary medical online, dictionary medical
terminology, dictionary free medical online, dictionary free
medical, dictionary medical terms, dictionary drug medical
medicine, dictionary health illustrated medical nursing
profession stedmans, dictionary English medical, dictionary
medical online terminology, dictionary encyclopedia medical
online, condition dictionary medical, dictionary medical,
dictionary drug medical, medical dictionary software, cyclopedic
dictionary index medical tabers thumb,
medical dictionary, online medical dictionary, medical
terminology dictionary
