A small rough spot on skin chronically exposed to
the sun, precancerous, can develop into a skin cancer called squamous cell carcinoma,
a process that typically takes years. Actinic keratoses occur most frequently in
fair-skinned people. Common locations are the face, scalp, back of the neck, upper
chest, forearm and back of the hand.
Prevention is by minimizing sun exposure. Treatments include cryosurgery (freezing
them with liquid nitrogen), cutting them away, burning them, putting 5-fluorouracil
(5-FU) on them, and photodynamic therapy (which involves injecting into the bloodstream
a chemical that collects in actinic keratoses and makes them more sensitive to exposure
to a specialized form of light).
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