Juvenile myelomonocytic leukemia definition - medical term
Abbreviated JMML. A rare cancer of the
myeloid cells in the bone marrow, accounting for less than 1% of all childhood leukemia.
J MML is most common in children under four years of age, especially those with
genetic disorders called neurofibromatosis 1 (NF1) and Noonan syndrome. Up to 14%
of cases of JMML occur in children with NF1.
Few approaches other than hematopoietic stem cell transplantation have resulted
in long-term survival for this disease. JMML was formerly called juvenile chronic
myelogenous leukemia (juvenile chronic myeloid leukemia, juvenile CML or JCML).
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