A genetic form of angioedema. (Ang ioedema is also
referred to as Quinke's disease.) Persons with it are born lacking an inhibitor
protein (called C1 esterase inhibitor) that normally prevents activation of a cascade
of proteins leading to the swelling of angioedema. Patients can develop recurrent
attacks of swollen tissues, pain in the abdomen, and swelling of the voice box (larynx)
which can compromise breathing. The diagnosis is suspected with a history of recurrent
angioedema. It is confirmed by finding abnormally low levels of C1 esterase inhibitor
in the blood. Treatment options include antihistamines and male steroids (androgens)
that can also prevent the recurrent attacks. Also called hereditary angioneurotic
edema.
Common Misspellings: hereditary angiodema, hereditory angioedema, hereditory
angiodema
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