An X chromosome with a heritable fragile site associated
with a frequent form of mental retardation -- the fragile X syndrome.
The fragile X chromosome was first sighted by Dr. Herbert A. Lubs in 1969 who
termed it the "marker X.". The fragile X is also called FRAXA. It was the first
fragile site found on the X chromosome.
The fragile X chromosome is due to a trinucleotide repeat sequence (a recurring
motif of 3 bases) in the DNA at that spot.
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