< b>Fissure: A cleft or groove. A fissure can be normal or abnormal.
A fissure in the cerebral cortex is a normal feature. It is a deep fold that
involves the entire thickness of the brain wall.
A fissure in the anus is distinctly abnormal. It is a painful crack in the edge
of the anus and is very painful. Also called an anal fissure or fissure in ano.
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