An inborn error of metabolism asso ciated with an
offensive body odor, the smell of rotting fish, due to the excessive excretion of
trimethylaminuria (TMA) in urine, sweat, and breath. Persons with TMA may experience
tachycardia (fast heart rate) and severe hypertension (high blood pressure) after
eating cheese (which contains tyramine) and after using nasal sprays containing
epinephrine. TMA is caused by a mutation (change) in the gene for an enzyme, flavin-containing
monooxygenase-3 (FMO3) encoded by a gene on chromosome #1. The FMO3 enzyme metabolizes
tyramine (which is in cheese). The syndrome is associated with various psychosocial
reactions, including social isolation, clinical depression and attempted suicide.
medical
dictionary, online medical dictionary, medical
terminology dictionary, free online medical
dictionary, medical dictionary, online medical
dictionary, medical terminology dictionary, free
online medical dictionary, dictionary medical,
dictionary medical online, dictionary medical
terminology, dictionary free medical online,
dictionary free medical, dictionary medical
terms, dictionary drug medical medicine,
dictionary health illustrated medical nursing
profession stedmans, dictionary English medical,
dictionary medical online terminology,
dictionary encyclopedia medical online,
condition dictionary medical, dictionary
medical, dictionary drug medical, medical
dictionary software, cyclopedic dictionary index
medical tabers thumb, medical dictionary, online
medical dictionary, medical terminology
dictionary
