Edema, hereditary angioneurotic definition - medical term
A genetic
form
of angioedema. (Angioedema is also referred to as Quinke's disease.) Persons
with it are born lacking an inhibitor protein (called C1 esterase inhibitor) that normally
prevents activation of a cascade of proteins leading to the swelling of angioedema.
Patients can develop recurrent attacks of swollen tissues, pain in the abdomen, and
swelling of the voice box (larynx) which can compromise breathing. The diagnosis is
suspected with a history of recurrent angioedema. It is confirmed by finding abnormally
low levels of C1 esterase inhibitor in the blood. Treatment options include antihistamines
and male steroids (androgens) that can also prevent the recurrent attacks. Also called
hereditary angioedema.
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