< b>Demarcation: A setting of limits; a boundary; marking the limits of,
delimiting; setting apart, separating. The word "demarcation" is used in medicine
mainly in the sense of determining and marking off boundaries. For example, the
surface demarcation in respect to damaged tissue can refer to the boundary between
the living tissue and the necrotic (dead) tissue.
"Demarcation" descends from the Italian verb "marcare" (to mark). It gave rise
to the Spanish "marcar" (to mark) from which came "demarcar" (to fix the boundary
of). In 1493, a Spanish noun, "demarcacion," was used to name the then-new meridian
dividing the Spanish Indies from the Portuguese Indies. About 1730 English speakers
began calling this boundary the "line of demarcation" and, in time, that came to
apply to other boundaries.
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