According to the National Academy
of S
ciences, the Recommended Dietary Allowances of zinc are 12
milligrams per day for women and 10 milligrams per day for men.
Food sources of zinc include meat including liver, eggs, seafood,
nuts and cereal.
Deficiency of zinc is associated with short stature, anemia,
increased pigmentation of skin (hyperpigmentation), enlarged liver
and spleen (hepatosplenomegaly), impaired gonadal function
(hypogonadism), impaired wound healing, and immune deficiency.
In a genetic disease called acrodermatitis enteropathica, there is
impaired zinc uptake from the intestine. The condition is
characterized by the simultaneous presence of dermatitis (skin
inflammation) and diarrhea. The skin on the cheeks, elbows and knees
and the tissues about the mouth and anus are inflamed. There is
balding of the scalp, eyebrows and eyelashes. Wound healing is
delayed. And there are recurrent bacterial and fungal infections due
to immune deficiency. The key laboratory finding is an abnormally low
blood zinc level reflecting the impaired zinc uptake. Treatment with
zinc is curative.
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