Definition of Deficiency, glucose-6-phosphate dehydrogenase
Deficiency, glucose-6-phosphate dehydrogenase (G6PD) definition - medical term
Deficiency
of G
6PD is the commonest disease-causing enzyme defect in humans affecting an estimated
400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency
develop anemia due to breakup of their red blood cells when they are exposed to oxidant
drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones,
naphthalene moth balls, or fava beans.
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