< b>Carcinoid syndrome: A syndrome due to carcinoid tumor which secretes
large amounts of the hormone serotonin. The syndrome is directly due to the serotonin.
Features include flushing and blushing, swelling of the face (especially around
the eyes), flat angiomas (little collections of dilated blood vessels) on the skin,
diarrhea, bronchial spasm, rapid pulse, low blood pressure and tricuspid and pulmonary
stenosis (narrowing of the tricuspid and pulmonic valves of the heart), often with
regurgitation.
Carcinoid tumor usually arises in the gastrointestinal tract, anywhere between
the stomach and the rectum (the favorite spot is in the appendix) and from there
may metastasize (spread) to the liver. In the liver the tumor produces and releases
large quantities of serotonin into the systemic bloodstream.
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