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Definition of Cancer, bile duct

Cancer, bile duct definition - medical term

The part of the bile duct that is outside the liver is called the extrahepatic bile duct. Bile, a fluid made by the liver that breaks down fats during digestion, is stored in the gallbladder. When food is being broken down in the intestines, bile is released from the gallbladder through the bile duct to the first part of the small intestine.

The symptoms of bile duct cancer include yellowing of the skin (jaundice), pain in the abdomen, fever, and itching.

Several different tests may be utilized to detect bile duct cancer. These may include an ultrasound (a test that uses sound waves to find tumors), a CT (a computed tomographic) scan, a special type of x-ray that uses a computer to make a picture of the inside of the abdomen) and an MRI (magnetic resonance imaging which uses magnetic waves to make a picture of the inside of the abdomen).

A test called an ERCP (endoscopic retrograde cholangiopancreatography) may be done. A flexible tube is put down the throat, through the stomach, and into the small intestine. Radiographic dye can then be injected into the bile duct system.

PTC (percutaneous transhepatic cholangiography) is another test that can help find cancer of the extrahepatic bile duct. During this test, a thin needle is put into the liver through the right side of the patient. Dye is injected through the needle into the bile duct in the liver so that blockages can be seen on x-rays.

If abnormal tissue is found, the doctor may remove a small amount of fluid or tissue from the bile duct and look at it under the microscope for cancer cells. This biopsy procedure is usually done during the PTC or ERCP.

Because it is sometimes hard to tell whether a patient has cancer or another disease, surgery may be needed. If extrahepatic bile duct cancer is found, further tests are done to see if the cancer cells have spread to other parts of the body. This is called staging the cancer. The stage of the cancer is important to the treatment plan and prognosis (outlook). The following stages are commonly used for extrahepatic bile duct cancer:

• Localized: The cancer is only in the area where it began and it can be removed by surgery.
• Unresectable: The cancer cannot be completely removed (resected) by surgery. The cancer may have spread to nearby organs and lymph nodes or to other parts of the body.
• Recurrent: This means the cancer has come back (recurred) after it has been treated. It may come back in the bile duct or in another part of the body.

The treatments for bile duct cancer include: surgery (taking out the cancer or taking steps to relieve symptoms caused by the cancer), radiation therapy (using high-dose x-rays to kill the cancer cells); and chemotherapy (using drugs to kill cancer cells).

The chances of recovery and the choice of treatment depend on the location of the cancer in the bile duct, the stage of the cancer and the patient's general health.

Professional Summary definition - medical term