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Definition of CADASIL
CADASIL definition - medical term
C
erebral
A
utosomal
D
ominant
A
rteriopathy
with
S
ubcortical
I
nfarcts and
L
eukoencephalopathy. An inherited
form of vascular dementia that strikes relatively young adults of both sexes and
is characterized by multiple strokes, dementia, migraine-like headaches, and psychiatric
disturbances. CADASIL is due to mutation of a gene called NOTCH3 located on chromosome
19. Also called hereditary multi-infarct dementia.
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