provides a comprehensive look
at the who, what, when and how of Barrett's esophagus
< b>Barrett's esophagus: A complication of severe chronic GERD (gastrointestinal
reflux disease) involving changes in the cells of the tissue that line the bottom
of the esophagus. These esophageal cells become irritated when the contents of the
stomach back up (refluxes) and there is a small but definite increased risk of adenocarcinoma
(cancer) of the esophagus. The diagnosis of Barrett esophagus rests upon seeing
(through endoscopy) a pink esophageal lining (mucosa) that extends a short distance
(usually less than 2.5 inches) up the esophagus from the gastroesophageal junction
and finding intestinal type cells (goblet cells) on biopsy of the lining. Treatment
is, in general, essentially the same as for GERD both medically (with acid-suppression
drugs) and surgically (with fundoplication).
Named after Norman Rupert Barrett (1903-1979), an eminent thoracic surgeon born
in Australia who studied medicine and practiced in Britain.
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